In the first match of the day on Arthur Ashe Stadium, Pegula dropped only three of her first-serve points and never faced a break point. The 2024 runner-up, who is seeking her maiden major title as well as top spot in the rankings, booked a meeting with 2021 finalist Leylah Fernandez.

Wildcard Kenin has struggled as injuries and illness saw her tumble down the rankings after her breakthrough 2020 Australian Open win and she was never able to get a foothold in the match as she suffered yet another early exit from her domestic major.

Kenin handed her opponent the break with a double fault in the opening game and Pegula broke her again on set point with a fine forehand before slamming her foot down on the gas.

The runner-up at the Cincinnati tune-up tournament was near flawless as she won the first five games of the second set, producing just two unforced errors before closing it out with an unreturnable serve.

"I'm going for my spots, I'm going pretty big on second serves," said Pegula, adding that she had put effort into adding more firepower to her serve. "Really excited when I can practise something and it pays off in a match."